Structural Basis for Transcriptional Start Site Control of HIV-1 RNA Fate

Heterogeneous transcriptional start site usage by HIV-1 produces 5’-capped RNAs beginning with one, two, or three 5’-guanosines ((Cap)1G, (Cap)2G, (Cap)3G, respectively) that are either selected for packaging as genomes ((Cap)1G) or retained in cells as translatable mRNAs ((Cap)2G/(Cap)3G). To under...

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Publicado no:Science
Main Authors: Brown, Joshua D., Kharytonchyk, Siarhei, Chaudry, Issac, Iyer, Aishwarya S., Carter, Hannah, Becker, Ghazal, Desai, Yash, Glang, Lindsay, Choi, Seung H., Singh, Karndeep, Lopresti, Michael W., Orellana, Matthew, Rodriguez, Tatiana, Oboh, Ubiomo, Hijji, Jana, Ghinger, Frances Grace, Stewart, Kailan, Francis, Dillion, Edwards, Bryce, Chen, Patrick, Case, David A., Telesnitsky, Alice, Summers, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7351118/
https://ncbi.nlm.nih.gov/pubmed/32327595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaz7959
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