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A massively parallel reporter assay dissects the influence of chromatin structure on cis-regulatory activity
A gene’s position in the genome can profoundly affect its expression because regional differences in chromatin modulate the activity of locally acting cis-regulatory sequences (CRSs). Here we study how CRSs and regional chromatin act in concert on a genome-wide scale. We present a massively parallel...
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| Gepubliceerd in: | Nat Biotechnol |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7351048/ https://ncbi.nlm.nih.gov/pubmed/30451991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.4285 |
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