Uremic Toxic Blood-Brain Barrier Disruption Mediated by AhR Activation Leads to Cognitive Impairment during Experimental Renal Dysfunction

BACKGROUND: Uremic toxicity may play a role in the elevated risk of developing cognitive impairment found among patients with CKD. Some uremic toxins, like indoxyl sulfate, are agonists of the transcription factor aryl hydrocarbon receptor (AhR), which is widely expressed in the central nervous syst...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Am Soc Nephrol
मुख्य लेखकों: Bobot, Mickaël, Thomas, Laurent, Moyon, Anaïs, Fernandez, Samantha, McKay, Nathalie, Balasse, Laure, Garrigue, Philippe, Brige, Pauline, Chopinet, Sophie, Poitevin, Stéphane, Cérini, Claire, Brunet, Philippe, Dignat-George, Françoise, Burtey, Stéphane, Guillet, Benjamin, Hache, Guillaume
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Nephrology 2020
विषय:
Basic Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7350986/
https://ncbi.nlm.nih.gov/pubmed/32527975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019070728
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