Bone marrow mesenchymal stem cell-derived exosomes protect cartilage damage and relieve knee osteoarthritis pain in a rat model of osteoarthritis

BACKGROUND: This study aimed to investigate the effect of bone marrow mesenchymal stem cell (BMSC)-derived exosome injection on cartilage damage and pain relief in both in vitro and in vivo models of osteoarthritis (OA). METHODS: The BMSCs were extracted from rat bone marrow of the femur and tibia....

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: He, Lei, He, Tianwei, Xing, Jianghao, Zhou, Qing, Fan, Lei, Liu, Can, Chen, Yuyong, Wu, Depeng, Tian, Zhenming, Liu, Bin, Rong, Limin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7350730/
https://ncbi.nlm.nih.gov/pubmed/32650828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01781-w
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