Llwytho...
Genes adapt to outsmart gene-targeting strategies in mutant mouse strains by skipping exons to reinitiate transcription and translation
BACKGROUND: Gene disruption in mouse embryonic stem cells or zygotes is a conventional genetics approach to identify gene function in vivo. However, because different gene disruption strategies use different mechanisms to disrupt genes, the strategies can result in diverse phenotypes in the resultin...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Genome Biol |
|---|---|
| Prif Awduron: | , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
BioMed Central
2020
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7350591/ https://ncbi.nlm.nih.gov/pubmed/32646486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02086-0 |
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