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Chemical Modification of Aptamers for Increased Binding Affinity in Diagnostic Applications: Current Status and Future Prospects

Aptamers are short single stranded DNA or RNA oligonucleotides that can recognize analytes with extraordinary target selectivity and affinity. Despite their promising properties and diagnostic potential, the number of commercial applications remains scarce. In order to endow them with novel recognit...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Elskens, Jan P., Elskens, Joke M., Madder, Annemieke
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7350236/
https://ncbi.nlm.nih.gov/pubmed/32630547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124522
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