Experimentally Determined Long Intrinsically Disordered Protein Regions Are Now Abundant in the Protein Data Bank

Intrinsically disordered protein regions are commonly defined from missing electron density in X-ray structures. Experimental evidence for long disorder regions (LDRs) of at least 30 residues was so far limited to manually curated proteins. Here, we describe a comprehensive and large-scale analysis...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Monzon, Alexander Miguel, Necci, Marco, Quaglia, Federica, Walsh, Ian, Zanotti, Giuseppe, Piovesan, Damiano, Tosatto, Silvio C. E.
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7349999/
https://ncbi.nlm.nih.gov/pubmed/32599863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124496
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