Inhibition of ABCC6 Transporter Modifies Cytoskeleton and Reduces Motility of HepG2 Cells via Purinergic Pathway

ABCC6, belonging to sub-family C of ATP-binding cassette transporter, is an ATP-dependent transporter mainly present in the basolateral plasma membrane of hepatic and kidney cells. Although the substrates transported are still uncertain, ABCC6 has been shown to promote ATP release. The extracellular...

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Published in:Cells
Main Authors: Ostuni, Angela, Carmosino, Monica, Miglionico, Rocchina, Abruzzese, Vittorio, Martinelli, Fabio, Russo, Daniela, Laurenzana, Ilaria, Petillo, Agata, Bisaccia, Faustino
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7349786/
https://ncbi.nlm.nih.gov/pubmed/32517079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061410
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