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ABCC6 knockdown in HepG2 cells induces a senescent-like cell phenotype
BACKGROUND: Pseudoxanthoma elasticum (PXE) is characterized by progressive ectopic mineralization of elastic fibers in dermal, ocular and vascular tissues. No effective treatment exists. It is caused by inactivating mutations in the gene encoding for the ATP-binding cassette, sub-family C member 6 t...
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| Publicado no: | Cell Mol Biol Lett |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5415800/ https://ncbi.nlm.nih.gov/pubmed/28536638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11658-017-0036-2 |
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