ABCC6 knockdown in HepG2 cells induces a senescent-like cell phenotype

BACKGROUND: Pseudoxanthoma elasticum (PXE) is characterized by progressive ectopic mineralization of elastic fibers in dermal, ocular and vascular tissues. No effective treatment exists. It is caused by inactivating mutations in the gene encoding for the ATP-binding cassette, sub-family C member 6 t...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Mol Biol Lett
Main Authors: Miglionico, Rocchina, Ostuni, Angela, Armentano, Maria Francesca, Milella, Luigi, Crescenzi, Elvira, Carmosino, Monica, Bisaccia, Faustino
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Short Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415800/
https://ncbi.nlm.nih.gov/pubmed/28536638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11658-017-0036-2
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