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Computational Model Reveals a Stochastic Mechanism behind Germinal Center Clonal Bursts
Germinal centers (GCs) are specialized compartments within the secondary lymphoid organs where B cells proliferate, differentiate, and mutate their antibody genes in response to the presence of foreign antigens. Through the GC lifespan, interclonal competition between B cells leads to increased affi...
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| Publicado no: | Cells |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7349200/ https://ncbi.nlm.nih.gov/pubmed/32532145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061448 |
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