The S1P–S1PR Axis in Neurological Disorders—Insights into Current and Future Therapeutic Perspectives

Sphingosine 1-phosphate (S1P), derived from membrane sphingolipids, is a pleiotropic bioactive lipid mediator capable of evoking complex immune phenomena. Studies have highlighted its importance regarding intracellular signaling cascades as well as membrane-bound S1P receptor (S1PR) engagement in va...

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Vydáno v:Cells
Hlavní autoři: Lucaciu, Alexandra, Brunkhorst, Robert, Pfeilschifter, Josef M., Pfeilschifter, Waltraud, Subburayalu, Julien
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7349054/
https://ncbi.nlm.nih.gov/pubmed/32580348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061515
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