Development of Cellular Models to Study Efficiency and Safety of Gene Edition by Homologous Directed Recombination Using the CRISPR/Cas9 System

In spite of the enormous potential of CRISPR/Cas in basic and applied science, the levels of undesired genomic modifications cells still remain mostly unknown and controversial. Nowadays, the efficiency and specificity of the cuts generated by CRISPR/Cas is the main concern. However, there are also...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Sánchez-Hernández, Sabina, Aguilar-González, Araceli, Guijarro-Albaladejo, Beatriz, Maldonado-Pérez, Noelia, Ramos-Hernández, Iris, Cortijo-Gutiérrez, Marina, Sánchez Martín, Rosario María, Benabdellah, Karim, Martin, Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7349026/
https://ncbi.nlm.nih.gov/pubmed/32570971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061492
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