The BMP Receptor 2 in Pulmonary Arterial Hypertension: When and Where the Animal Model Matches the Patient

Background: Mutations in bone morphogenetic protein receptor type II (BMPR2) are leading to the development of hereditary pulmonary arterial hypertension (PAH). In non-hereditary forms of PAH, perturbations in the transforming growth factor-β (TGF-β)/BMP-axis are believed to cause deficient BMPR2 si...

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Xehetasun bibliografikoak
Argitaratua izan da:Cells
Egile Nagusiak: Happé, Chris, Kurakula, Kondababu, Sun, Xiao-Qing, da Silva Goncalves Bos, Denielli, Rol, Nina, Guignabert, Christophe, Tu, Ly, Schalij, Ingrid, Wiesmeijer, Karien C., Tura-Ceide, Olga, Vonk Noordegraaf, Anton, de Man, Frances S., Bogaard, Harm Jan, Goumans, Marie-José
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2020
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Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348993/
https://ncbi.nlm.nih.gov/pubmed/32521690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061422
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