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Large-Scale Drug Screening in Patient-Derived IDH(mut) Glioma Stem Cells Identifies Several Efficient Drugs among FDA-Approved Antineoplastic Agents
The discovery of the isocitrate dehydrogenase (IDH) mutation in glioma led to a paradigm shift on how we see glioma biology. Difficulties in cultivating IDH mutant glioma stem cells (IDH(mut) GSCs) resulted in a paucity of preclinical models in IDH(mut) glioma, limiting the discovery of new effectiv...
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| Publicat a: | Cells |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7348988/ https://ncbi.nlm.nih.gov/pubmed/32503220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061389 |
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