DDIS-22. DRUG SCREEN IN PATIENT-DERIVED IDHMUT GLIOMA STEM CELLS IDENTIFIES SEVERAL FDA-APPROVED ANTINEOPLASTIC AGENTS

OBJECTIVE: The discovery of the Isocitrate Dehydrogenase (IDH) mutation in glioma has led to a paradigm shift on how we see glioma biology. While it is clear, that IDH mutated (IDHmut) and wildtype (IDHwt) tumors have to be viewed as separate entities, the underlying biological differences are still...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Dao Trong, Philip, Pusch, Stefan, Unterberg, Andreas, Herold-Mende, Christel, Warta, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Drug Discovery
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847371/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.273
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