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DDIS-22. DRUG SCREEN IN PATIENT-DERIVED IDHMUT GLIOMA STEM CELLS IDENTIFIES SEVERAL FDA-APPROVED ANTINEOPLASTIC AGENTS

OBJECTIVE: The discovery of the Isocitrate Dehydrogenase (IDH) mutation in glioma has led to a paradigm shift on how we see glioma biology. While it is clear, that IDH mutated (IDHmut) and wildtype (IDHwt) tumors have to be viewed as separate entities, the underlying biological differences are still...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Dao Trong, Philip, Pusch, Stefan, Unterberg, Andreas, Herold-Mende, Christel, Warta, Rolf
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847371/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.273
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