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Protective Effects of SIRT6 Overexpression against DSS-Induced Colitis in Mice

Sirtuin 6 (SIRT6), as a NAD + -dependent deacetylase, plays an indispensable role in the regulation of health and physiology. Loss of SIRT6 causes spontaneous colitis in mice and makes intestinal epithelial cells prone to stress. However, whether SIRT6 overexpression increases resistance to colitis...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Xu, Kang, Guo, Yannan, Ping, Lu, Qiu, Ying, Liu, Qingfei, Li, Zhongchi, Wang, Zhao
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348883/
https://ncbi.nlm.nih.gov/pubmed/32580272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061513
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