Glycogen Synthase Kinase-3β Facilitates Cytokine Production in 12-O-Tetradecanoylphorbol-13-Acetate/Ionomycin-Activated Human CD4(+) T Lymphocytes

Cytokines are the major immune regulators secreted from activated CD4(+) T lymphocytes that activate adaptive immunity to eradicate nonself cells, including pathogens, tumors, and allografts. The regulation of glycogen synthase kinase (GSK)-3β, a serine/threonine kinase, controls cytokine production...

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Detalhes bibliográficos
Publicado no:Cells
Principais autores: Tsai, Cheng-Chieh, Tsai, Chin-Kun, Tseng, Po-Chun, Lin, Chiou-Feng, Chen, Chia-Ling
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348852/
https://ncbi.nlm.nih.gov/pubmed/32521784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061424
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