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Altered Transcription Factor Binding and Gene Bivalency in Islets of Intrauterine Growth Retarded Rats

Intrauterine growth retardation (IUGR), which induces epigenetic modifications and permanent changes in gene expression, has been associated with the development of type 2 diabetes. Using a rat model of IUGR, we performed ChIP-Seq to identify and map genome-wide histone modifications and gene dysreg...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cells
Asıl Yazarlar: Lien, Yu-Chin, Wang, Paul Zhiping, Lu, Xueqing Maggie, Simmons, Rebecca A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348746/
https://ncbi.nlm.nih.gov/pubmed/32527043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061435
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