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Altered Transcription Factor Binding and Gene Bivalency in Islets of Intrauterine Growth Retarded Rats

Intrauterine growth retardation (IUGR), which induces epigenetic modifications and permanent changes in gene expression, has been associated with the development of type 2 diabetes. Using a rat model of IUGR, we performed ChIP-Seq to identify and map genome-wide histone modifications and gene dysreg...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Lien, Yu-Chin, Wang, Paul Zhiping, Lu, Xueqing Maggie, Simmons, Rebecca A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348746/
https://ncbi.nlm.nih.gov/pubmed/32527043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061435
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