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A case of Usher syndrome type IIA caused by a rare USH2A homozygous frameshift variant with maternal uniparental disomy (UPD) in a Chinese family

Usher syndrome encompasses a group of genetically and clinically heterogeneous autosomal recessive disorders with hearing deficiencies and retinitis pigmentosa. The mechanisms underlying the Usher syndrome are highly variable. In the present study, a Chinese family with Usher syndrome was recruited....

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Pubblicato in:J Cell Mol Med
Autori principali: Fu, Jiewen, Shen, Shiyi, Cheng, Jingliang, Lv, Hongbin, Fu, Junjiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348175/
https://ncbi.nlm.nih.gov/pubmed/32449591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15405
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