Dabigatran ameliorates airway smooth muscle remodeling in asthma by modulating Yes‐associated protein

Accumulating evidence indicates that thrombin, the major effector of the coagulation cascade, plays an important role in the pathogenesis of asthma. Interestingly, dabigatran, a drug used in clinical anticoagulation, directly inhibits thrombin activity. The aim of this study was to investigate the e...

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Pubblicato in:J Cell Mol Med
Autori principali: Deng, Zhenan, Xie, Haojun, Cheng, Weiying, Zhang, Meihong, Liu, Jie, Huo, Yating, Liao, Yulin, Cheng, Yuanxiong
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348141/
https://ncbi.nlm.nih.gov/pubmed/32542982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15485
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