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Dabigatran ameliorates airway smooth muscle remodeling in asthma by modulating Yes‐associated protein

Accumulating evidence indicates that thrombin, the major effector of the coagulation cascade, plays an important role in the pathogenesis of asthma. Interestingly, dabigatran, a drug used in clinical anticoagulation, directly inhibits thrombin activity. The aim of this study was to investigate the e...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Deng, Zhenan, Xie, Haojun, Cheng, Weiying, Zhang, Meihong, Liu, Jie, Huo, Yating, Liao, Yulin, Cheng, Yuanxiong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348141/
https://ncbi.nlm.nih.gov/pubmed/32542982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15485
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