Tumour budding, poorly differentiated clusters, and T-cell response in colorectal cancer

BACKGROUND: Tumour budding and poorly differentiated clusters (PDC) represent forms of tumour invasion. We hypothesised that T-cell densities (reflecting adaptive anti-tumour immunity) might be inversely associated with tumour budding and PDC in colorectal carcinoma. METHODS: Utilising 915 colon and...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Fujiyoshi, Kenji, Väyrynen, Juha P., Borowsky, Jennifer, Papke, David J., Arima, Kota, Haruki, Koichiro, Kishikawa, Junko, Akimoto, Naohiko, Ugai, Tomotaka, Lau, Mai Chan, Gu, Simeng, Shi, Shanshan, Zhao, Melissa, Da Silva, Annacarolina Fabiana Lucia, Twombly, Tyler S., Nan, Hongmei, Meyerhardt, Jeffrey A., Song, Mingyang, Zhang, Xuehong, Wu, Kana, Chan, Andrew T., Fuchs, Charles S., Lennerz, Jochen K., Giannakis, Marios, Nowak, Jonathan A., Ogino, Shuji
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347996/
https://ncbi.nlm.nih.gov/pubmed/32652320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102860
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