Tumour budding, poorly differentiated clusters, and T-cell response in colorectal cancer

BACKGROUND: Tumour budding and poorly differentiated clusters (PDC) represent forms of tumour invasion. We hypothesised that T-cell densities (reflecting adaptive anti-tumour immunity) might be inversely associated with tumour budding and PDC in colorectal carcinoma. METHODS: Utilising 915 colon and...

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Vydáno v:EBioMedicine
Hlavní autoři: Fujiyoshi, Kenji, Väyrynen, Juha P., Borowsky, Jennifer, Papke, David J., Arima, Kota, Haruki, Koichiro, Kishikawa, Junko, Akimoto, Naohiko, Ugai, Tomotaka, Lau, Mai Chan, Gu, Simeng, Shi, Shanshan, Zhao, Melissa, Da Silva, Annacarolina Fabiana Lucia, Twombly, Tyler S., Nan, Hongmei, Meyerhardt, Jeffrey A., Song, Mingyang, Zhang, Xuehong, Wu, Kana, Chan, Andrew T., Fuchs, Charles S., Lennerz, Jochen K., Giannakis, Marios, Nowak, Jonathan A., Ogino, Shuji
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
Témata:
Research paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347996/
https://ncbi.nlm.nih.gov/pubmed/32652320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102860
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