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Inhalation exposure to cigarette smoke and inflammatory agents induces epigenetic changes in the lung

Smoking-related lung tumors are characterized by profound epigenetic changes including scrambled patterns of DNA methylation, deregulated histone acetylation, altered gene expression levels, distorted microRNA profiles, and a global loss of cytosine hydroxymethylation marks. Here, we employed an enh...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Seiler, Christopher L., Song, J ung Min, Kotandeniya, Delshanee, Chen, Jianji, Kono, Thomas J. Y., Han, Qiyuan, Colwell, Mathia, Auch, Benjamin, Sarver, Aaron L., Upadhyaya, Pramod, Ren, Yanan, Faulk, Christopher, De Flora, Silvio, La Maestra, Sebastiano, Chen, Yue, Kassie, Fekadu, Tretyakova, Natalia Y.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347915/
https://ncbi.nlm.nih.gov/pubmed/32647312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67502-8
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