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The 3D Brain Unit Network Model to Study Spatial Brain Drug Exposure under Healthy and Pathological Conditions

PURPOSE: We have developed a 3D brain unit network model to understand the spatial-temporal distribution of a drug within the brain under different (normal and disease) conditions. Our main aim is to study the impact of disease-induced changes in drug transport processes on spatial drug distribution...

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Detalhes bibliográficos
Publicado no:Pharm Res
Main Authors: Vendel, Esmée, Rottschäfer, Vivi, de Lange, Elizabeth C.M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347686/
https://ncbi.nlm.nih.gov/pubmed/32648115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-020-2760-y
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