Celastrol inhibits ezrin-mediated migration of hepatocellular carcinoma cells

Progression of hepatocellular carcinoma involves multiple genetic and epigenetic alterations that promote cancer invasion and metastasis. Our recent study revealed that hyperphosphorylation of ezrin promotes intrahepatic metastasis in vivo and cell migration in vitro. Celastrol is a natural product...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Du, Shihao, Song, Xiaoyu, Li, Yuan, Cao, Yalei, Chu, Fuhao, Durojaye, Olanrewaju Ayodeji, Su, Zeqi, Shi, Xiaoguang, Wang, Jing, Cheng, Juan, Wang, Tangshun, Gao, Xiang, Chen, Yan, Zeng, Wuzhekai, Wang, Fengsong, Wang, DongMei, Liu, Xing, Ding, Xia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347585/
https://ncbi.nlm.nih.gov/pubmed/32647287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68238-1
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