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TGF-β regulates Sca-1 expression and plasticity of pre-neoplastic mammary epithelial stem cells

The epithelial-mesenchymal plasticity, in tight association with stemness, contributes to the mammary gland homeostasis, evolution of early neoplastic lesions and cancer dissemination. Focused on cell surfaceome, we used mouse models of pre-neoplastic mammary epithelial and cancer stem cells to reve...

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書目詳細資料
發表在:Sci Rep
Main Authors: Remšík, Ján, Pícková, Markéta, Vacek, Ondřej, Fedr, Radek, Binó, Lucia, Hampl, Aleš, Souček, Karel
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347574/
https://ncbi.nlm.nih.gov/pubmed/32647280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67827-4
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