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TGF-β regulates Sca-1 expression and plasticity of pre-neoplastic mammary epithelial stem cells

The epithelial-mesenchymal plasticity, in tight association with stemness, contributes to the mammary gland homeostasis, evolution of early neoplastic lesions and cancer dissemination. Focused on cell surfaceome, we used mouse models of pre-neoplastic mammary epithelial and cancer stem cells to reve...

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Publicado en:Sci Rep
Autores principales: Remšík, Ján, Pícková, Markéta, Vacek, Ondřej, Fedr, Radek, Binó, Lucia, Hampl, Aleš, Souček, Karel
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347574/
https://ncbi.nlm.nih.gov/pubmed/32647280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67827-4
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