Natural and engineered chemokine (C-X-C motif) receptor 4 agonists prevent acute respiratory distress syndrome after lung ischemia–reperfusion injury and hemorrhage

We compared therapeutic properties of natural and engineered chemokine (C-X-C motif) receptor 4 (CXCR4) agonists in a rat acute respiratory distress syndrome (ARDS) model utilizing the PaO(2)/FiO(2)-ratio as a clinically relevant primary outcome criterion. Ventilated rats underwent unilateral lung i...

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Publicado en:Sci Rep
Main Authors: Babu, Favin S., Liang, Xiaomei, Enten, Garrett A., DeSantis, Anthony J., Volkman, Brian F., Gao, Xianlong, Majetschak, Matthias
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347544/
https://ncbi.nlm.nih.gov/pubmed/32647374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68425-0
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