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The short-chain free fatty acid receptor FFAR3 is expressed and potentiates contraction in human airway smooth muscle

Emerging evidence suggests that gut microbiota-derived short-chain fatty acids (SCFAs; acetate, propionate, and butyrate) are important modulators of the inflammatory state in diseases such as asthma. However, the functional expression of the G(i) protein-coupled free fatty acid receptors (FFAR2/GPR...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Physiol Lung Cell Mol Physiol
Hauptverfasser: Mizuta, Kentaro, Sasaki, Haruka, Zhang, Yi, Matoba, Atsuko, Emala, Charles W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347267/
https://ncbi.nlm.nih.gov/pubmed/32209026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00357.2019
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