Development of an ELISA for the quantification of mycolactone, the cytotoxic macrolide toxin of Mycobacterium ulcerans

Mycolactones, macrolide cytotoxins, are key virulence factors of Mycobacterium ulcerans, the etiological agent of the chronic necrotizing skin disease Buruli ulcer. There is urgent need for a simple point-of-care laboratory test for Buruli ulcer and mycolactone represents a promising target for the...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Warryn, Louisa, Dangy, Jean-Pierre, Gersbach, Philipp, Gehringer, Matthias, Schäfer, Anja, Ruf, Marie-Thérèse, Ruggli, Nicolas, Altmann, Karl-Heinz, Pluschke, Gerd
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347236/
https://ncbi.nlm.nih.gov/pubmed/32589646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008357
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