Antibody-Mediated Neutralization of the Exotoxin Mycolactone, the Main Virulence Factor Produced by Mycobacterium ulcerans

BACKGROUND: Mycolactone, the macrolide exotoxin produced by Mycobacterium ulcerans, causes extensive tissue destruction by inducing apoptosis of host cells. In this study, we aimed at the production of antibodies that could neutralize the cytotoxic activities of mycolactone. METHODOLOGY/PRINCIPAL FI...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Dangy, Jean-Pierre, Scherr, Nicole, Gersbach, Philipp, Hug, Melanie N., Bieri, Raphael, Bomio, Claudio, Li, Jun, Huber, Sylwia, Altmann, Karl-Heinz, Pluschke, Gerd
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924874/
https://ncbi.nlm.nih.gov/pubmed/27351976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004808
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados