Correlation of pyroglutamate amyloid β and ptau Ser202/Thr205 levels in Alzheimer’s disease and related murine models

Senile plaques frequently contain Aβ-pE(3), a N-terminally truncated Aβ species that is more closely linked to AD compared to other Aβ species. Tau protein is highly phosphorylated at several residues in AD, and specifically phosphorylation at Ser202/Thr205 is known to be increased in AD. Several st...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Neddens, Joerg, Daurer, Magdalena, Flunkert, Stefanie, Beutl, Kerstin, Loeffler, Tina, Walker, Lauren, Attems, Johannes, Hutter-Paier, Birgit
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347153/
https://ncbi.nlm.nih.gov/pubmed/32645028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0235543
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