Correlation of pyroglutamate amyloid β and ptau Ser202/Thr205 levels in Alzheimer’s disease and related murine models

Senile plaques frequently contain Aβ-pE(3), a N-terminally truncated Aβ species that is more closely linked to AD compared to other Aβ species. Tau protein is highly phosphorylated at several residues in AD, and specifically phosphorylation at Ser202/Thr205 is known to be increased in AD. Several st...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Neddens, Joerg, Daurer, Magdalena, Flunkert, Stefanie, Beutl, Kerstin, Loeffler, Tina, Walker, Lauren, Attems, Johannes, Hutter-Paier, Birgit
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347153/
https://ncbi.nlm.nih.gov/pubmed/32645028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0235543
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