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Insulin receptor preserves mitochondrial function by binding VDAC1 in insulin insensitive mucosal epithelial cells

Unlike many epithelial tissues, the corneal epithelium is insulin insensitive, meaning it does not require insulin for glucose uptake. In this study, we show that insulin differentially regulates mitochondrial respiration in two human mucosal epithelial cell types: insulin-insensitive corneal epithe...

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Bibliographic Details
Published in:FASEB J
Main Authors: Titone, Rossella, Robertson, Danielle M.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7346881/
https://ncbi.nlm.nih.gov/pubmed/31914671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901316RR
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