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Insulin mediates de novo nuclear accumulation of the IGF-1/insulin Hybrid Receptor in corneal epithelial cells

Insulin and insulin-like growth factor-1 (IGF-1) are present in human tears and likely play an important role in mediating ocular surface homeostasis. We previously characterized the IGF-1/insulin hybrid receptor (Hybrid–R) in corneal epithelial cells and found that it was activated by IGF-1 and not...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Titone, Rossella, Zhu, Meifang, Robertson, Danielle M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847585/
https://ncbi.nlm.nih.gov/pubmed/29531349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21031-7
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