Trimethylamine-N-oxide acutely increases cardiac muscle contractility

Cardiovascular disease is a major cause of morbidity and mortality among patients with chronic kidney disease (CKD). Trimethylamine-N-oxide (TMAO), a uremic metabolite that is elevated in the setting of CKD, has been implicated as a nontraditional risk factor for cardiovascular disease. While associ...

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Veröffentlicht in:Am J Physiol Heart Circ Physiol
Hauptverfasser: Oakley, Carlee I., Vallejo, Julian A., Wang, Derek, Gray, Mark A., Tiede-Lewis, LeAnn M., Shawgo, Tilitha, Daon, Emmanuel, Zorn, George, Stubbs, Jason R., Wacker, Michael J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7346532/
https://ncbi.nlm.nih.gov/pubmed/32243768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00507.2019
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