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Attenuation of CD4(+) T-cell function by human adenovirus type 35 is mediated by the knob protein

The complement-regulatory protein CD46 is the primary receptor for human adenovirus type 35 (HAdV-35) and can regulate human immune-cell activation. CD4(+) T-cells are critical for initiating and maintaining adaptive immunity elicited by infection or vaccination. It was reported previously that HAdV...

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Detalhes bibliográficos
Publicado no:J Gen Virol
Main Authors: Adams, William C., Berenson, Ronald J., Karlsson Hedestam, Gunilla B., Lieber, André, Koup, Richard A., Loré, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: Microbiology Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7346476/
https://ncbi.nlm.nih.gov/pubmed/22357750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.039222-0
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