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Lactate dehydrogenase expression modulates longevity and neurodegeneration in Drosophila melanogaster
Lactate dehydrogenase (LDH) catalyzes the conversion of glycolysis-derived pyruvate to lactate. Lactate has been shown to play key roles in brain energetics and memory formation. However, lactate levels are elevated in aging and Alzheimer’s disease patients, and it is not clear whether lactate plays...
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| Publicat a: | Aging (Albany NY) |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7346061/ https://ncbi.nlm.nih.gov/pubmed/32484787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103373 |
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