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MSH2 Overexpression Due to an Unclassified Variant in 3’-Untranslated Region in a Patient with Colon Cancer

Background: The loss or low expression of DNA mismatch repair (MMR) genes can result in genomic instability and tumorigenesis. One such gene, MSH2, is mutated or rearranged in Lynch syndrome (LS), which is characterized by a high risk of tumor development, including colorectal cancer. However, many...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Liccardo, Raffaella, Nolano, Antonio, Lambiase, Matilde, Della Ragione, Carlo, De Rosa, Marina, Izzo, Paola, Duraturo, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7345785/
https://ncbi.nlm.nih.gov/pubmed/32575404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8060167
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