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Novel Implications in Molecular Diagnosis of Lynch Syndrome

About 10% of total colorectal cancers are associated with known Mendelian inheritance, as Familial Adenomatous Polyposis (FAP) and Lynch syndrome (LS). In these cancer types the clinical manifestations of disease are due to mutations in high-risk alleles, with a penetrance at least of 70%. The LS is...

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Опубликовано в: :Gastroenterol Res Pract
Главные авторы: Liccardo, Raffaella, De Rosa, Marina, Izzo, Paola, Duraturo, Francesca
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5303590/
https://ncbi.nlm.nih.gov/pubmed/28250766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/2595098
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