How Does the CO(2) in Supercritical State Affect the Properties of Drug-Polymer Systems, Dissolution Performance and Characteristics of Tablets Containing Bicalutamide?

The increasing demand for novel drug formulations has caused the introduction of the supercritical fluid technology, CO(2) in particular, into pharmaceutical technology as a method enabling the reduction of particle size and the formation of inclusion complexes and solid dispersions. In this paper,...

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Veröffentlicht in:Materials (Basel)
Hauptverfasser: Antosik-Rogóż, Agata, Szafraniec-Szczęsny, Joanna, Chmiel, Krzysztof, Knapik-Kowalczuk, Justyna, Kurek, Mateusz, Gawlak, Karolina, Danesi, Vittorio P., Paluch, Marian, Jachowicz, Renata
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7344854/
https://ncbi.nlm.nih.gov/pubmed/32630453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ma13122848
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