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Relocation of Collapsed Forks to the Nuclear Pore Complex Depends on Sumoylation of DNA Repair Proteins and Permits Rad51 Association

Expanded CAG repeats form stem-loop secondary structures that lead to fork stalling and collapse. Previous work has shown that these collapsed forks relocalize to nuclear pore complexes (NPCs) in late S phase in a manner dependent on replication, the nucleoporin Nup84, and the Slx5 protein, which pr...

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Publicado en:Cell Rep
Autores principales: Whalen, Jenna M., Dhingra, Nalini, Wei, Lei, Zhao, Xiaolan, Freudenreich, Catherine H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7344339/
https://ncbi.nlm.nih.gov/pubmed/32402281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107635
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