Lorcaserin Alters Serotonin and Noradrenaline Tissue Content and Their Interaction With Dopamine in the Rat Brain

Lorcaserin is a preferential serotonin2C receptor (5-HT(2C)R) agonist effective to treat obesity that has also recently been proposed to treat addiction and epilepsy. Central dopamine (DA) mechanisms are likely involved in the lorcaserin mechanism of action, but other monoamines 5-HT and noradrenali...

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Bibliografische gegevens
Gepubliceerd in:Front Pharmacol
Hoofdauteurs: Di Giovanni, Giuseppe, Bharatiya, Rahul, Puginier, Emilie, Ramos, Marta, De Deurwaerdère, Salomé, Chagraoui, Abdeslam, De Deurwaerdère, Philippe
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2020
Onderwerpen:
Pharmacology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7344148/
https://ncbi.nlm.nih.gov/pubmed/32714188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00962
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