Lorcaserin Alters Serotonin and Noradrenaline Tissue Content and Their Interaction With Dopamine in the Rat Brain

Lorcaserin is a preferential serotonin2C receptor (5-HT(2C)R) agonist effective to treat obesity that has also recently been proposed to treat addiction and epilepsy. Central dopamine (DA) mechanisms are likely involved in the lorcaserin mechanism of action, but other monoamines 5-HT and noradrenali...

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Dades bibliogràfiques
Publicat a:Front Pharmacol
Autors principals: Di Giovanni, Giuseppe, Bharatiya, Rahul, Puginier, Emilie, Ramos, Marta, De Deurwaerdère, Salomé, Chagraoui, Abdeslam, De Deurwaerdère, Philippe
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7344148/
https://ncbi.nlm.nih.gov/pubmed/32714188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00962
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