Lorcaserin Alters Serotonin and Noradrenaline Tissue Content and Their Interaction With Dopamine in the Rat Brain

Lorcaserin is a preferential serotonin2C receptor (5-HT(2C)R) agonist effective to treat obesity that has also recently been proposed to treat addiction and epilepsy. Central dopamine (DA) mechanisms are likely involved in the lorcaserin mechanism of action, but other monoamines 5-HT and noradrenali...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Di Giovanni, Giuseppe, Bharatiya, Rahul, Puginier, Emilie, Ramos, Marta, De Deurwaerdère, Salomé, Chagraoui, Abdeslam, De Deurwaerdère, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7344148/
https://ncbi.nlm.nih.gov/pubmed/32714188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00962
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