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Ezetimibe protects against spinal cord injury by regulating autophagy and apoptosis through inactivation of PI3K/AKT/mTOR signaling

Spinal cord injury (SCI) is a severe traumatic disease of the central nervous system characterized by high incidence and disability rate. We aimed to investigate the therapeutic potential of Ezetimibe (Eze) in SCI and identify the underlying mechanisms. Acute SCI rat model was established by using t...

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Publicat a:Am J Transl Res
Autors principals: Chen, Gang, Li, Jiandong, Wang, Zhenyu, Liu, Wenge
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7344056/
https://ncbi.nlm.nih.gov/pubmed/32655800
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