Ezetimibe protects against spinal cord injury by regulating autophagy and apoptosis through inactivation of PI3K/AKT/mTOR signaling

Spinal cord injury (SCI) is a severe traumatic disease of the central nervous system characterized by high incidence and disability rate. We aimed to investigate the therapeutic potential of Ezetimibe (Eze) in SCI and identify the underlying mechanisms. Acute SCI rat model was established by using t...

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Vydáno v:Am J Transl Res
Hlavní autoři: Chen, Gang, Li, Jiandong, Wang, Zhenyu, Liu, Wenge
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7344056/
https://ncbi.nlm.nih.gov/pubmed/32655800
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