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Extracellular serine controls epidermal stem cell fate and tumor initiation
Tissue stem cells are the cell of origin for many malignancies. Metabolites regulate the balance between self-renewal and differentiation, but whether endogenous metabolic pathways or nutrient availability predispose stem cells to transformation remains unknown. Here, we address this question in epi...
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| Опубликовано в: : | Nat Cell Biol |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7343604/ https://ncbi.nlm.nih.gov/pubmed/32451440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-020-0525-9 |
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