APOE ε4 allele accelerates age-related multi-cognitive decline and white matter damage in non-demented elderly

Advanced age and apolipoprotein E (APOE) ε4 allele are both associated with increased risk of the Alzheimer’s disease (AD). However, the extent of the joint contribution of APOE ε4 allele and age on the brain white matter integrity, cognition and their relationship are unclear. We assessed the age-r...

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Publicado en:Aging (Albany NY)
Autores principales: Sun, Jinping, Zhu, Zhibao, Chen, Kewei, Wei, Dongfeng, Li, Xin, Li, He, Zhang, Junying, Chen, Xiaochun, Chen, Yaojing, Zhang, Zhanjun
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343443/
https://ncbi.nlm.nih.gov/pubmed/32572010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103367
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